As we mentioned in previous articles, infertility is defined as inability of a couple to conceive after 12 months of unprotected sexual intercourse or can not carry the pregnancy to term. It effects over 5 millions couple alone in the U. S. and many times more in the world. Because of unawareness of treatments, only 10% seeks help from professional specialist. In this article, we will discuss what is male infertility hypoosmotic swelling test (HOST) ??
I. Definition Hypoosmotic swelling test (HOST) is the test used to identify sperm membrane for structure integrity by examining how the sperm tail reacts to special sugar and salt. Only healthy sperm can react in this circumstance.
II. Procedure The HOS test was performed by mixing special sugar and salt in distilled water. The mixture was incubated and immediately examined under a microscope. The percentage of reacted sperm (curled tails) and non-reacted sperm (non-curled tails) were assessed.
III. Diagnosis 1. A sample sperm is considered normal if more than 60% response to the swollen spermatozoa. otherwise the tested sample is considered to have poor sperm membrane structure integrity. It is said the hypoosmotic swelling test result is predictive of the sperm penetration test. If the tested sample fail, it may need some other technical support to by-pass the sperm penetration process.
IV. Risk Although the hypoosmotic swelling test is less time consuming and can help to determine the the sperm fertilization capacity, the result is not 100% guaranteed. For the couple to conceive, it take more than the hypoosmotic swelling test for a successful pregnancy, please make sure that other health problems have been taking care of.
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